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What Is the Endocannabinoid System?

Exploring how the body’s natural network of receptors interacts with cannabinoids to maintain balance.

Understanding the Endocannabinoid System (ECS)

The endocannabinoid system (ECS) is a complex biological network found throughout the human body. It helps maintain internal balance, or homeostasis, by regulating various physiological processes such as appetite, memory, mood, and immune function.
The ECS is composed of three main parts:

  1. Endocannabinoids – Compounds naturally produced by the body that interact with cannabinoid receptors.

  2. Cannabinoid Receptors (CB1 and CB2) – Proteins located on the surface of cells throughout the body.

  3. Enzymes – Responsible for creating and breaking down endocannabinoids once they’ve carried out their function.

Cannabinoids from the cannabis plant—such as THC, CBD, and others—can interact with these same receptors, mimicking or influencing the body’s own endocannabinoids.

Terpenes and Cannabinoids: Working Together

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CB1 Receptors
CB1 receptors are primarily found in the brain and central nervous system, but they also exist in other tissues throughout the body.
 These receptors play a role in regulating key physiological and neurological functions such as:

  • Appetite

  • Motor activity and coordination

  • Pain perception

  • Short-term memory

  • Cognitive processing

CB2 Receptors

CB2 receptors are located mainly in the peripheral organs and are especially concentrated in cells associated with the immune system.
 They are also found in various other areas of the body, including:​

  • Adipose tissue

  • Bone

  • Cardiovascular system

  • Central nervous system

  • Eyes

  • Gut

  • Kidneys

  • ​​Liver

  • Pancreas

  • Reproductive system

  • Respiratory tract

  • Skeletal muscle

  • Skin

  • Tumors

Why Does This Matter? – The Entourage Effect

The endocannabinoid system (ECS) is a complex biological network found throughout the human body. It helps maintain internal balance, or homeostasis, by regulating various physiological processes such as appetite, memory, mood, and immune function.
The ECS is composed of three main parts:

  1. Endocannabinoids – Compounds naturally produced by the body that interact with cannabinoid receptors.

  2. Cannabinoid Receptors (CB1 and CB2) – Proteins located on the surface of cells throughout the body.

  3. Enzymes – Responsible for creating and breaking down endocannabinoids once they’ve carried out their function.

Cannabinoids from the cannabis plant—such as THC, CBD, and others—can interact with these same receptors, mimicking or influencing the body’s own endocannabinoids.

Commitment to Education

At Firelands Scientific, we believe understanding the science behind cannabis empowers patients and customers to make informed decisions. We are dedicated to providing educational resources that explain the biology of the plant, its interaction with the body, and the importance of quality, consistency, and transparency in every product we create.

Note: The information provided here is for educational purposes only and should not be considered medical advice.
 Please consult your recommending physician for questions related to qualifying conditions or treatment options.
 These statements have not been evaluated by the Food and Drug Administration. Products mentioned are not intended to diagnose, treat, cure, or prevent any disease.

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Solventless Guide

We use time-tested, mechanical methods to produce our solventless products while maintaining the highest standards of purity and consistency.

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Terpenes Guide

Discover how natural aromatic compounds give each cannabis strain its distinctive scent and character.

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